Wissenschaftliche Beiträge
2025
Eder, J., David, F. S., Illius, S., Rothe, N., Wekenborg, M. K., Walther, A., Penz, M., Jylhävä, J., Miller, R., Kirschbaum, C., & Alexander, N. (2025). Work-related stress and burnout: Is epigenetic aging the missing link? Clinical Epigenetics, 17, 148. https://doi.org/10.1186/s13148-025-01968-z
2024
Eder, J., Kräter, M., Kirschbaum, C., Gao, W., Wekenborg, M., Penz, M., Rothe, N., Guck, J., Wittwer, L. D., & Walther, A. (2024). Longitudinal associations between depressive symptoms and cell deformability: do glucocorticoids play a role? European Archives of Psychiatry and Clinical Neuroscience, 275, 1075–1085. https://doi.org/10.1007/s00406-024-01902-z
Matti, N., Mauczok, C., Eder, J., Wekenborg, M. K., Penz, M., Walther, A., Kirschbaum, C., Specht, M. B., & Rothe, N. (2024). Work-related stress and sleep quality – the mediating role of rumination: a longitudinal analysis. Somnologie. https://doi.org/10.1007/s11818-024-00481-4
2023
Verkuil, B., & Wekenborg, M. K. (2023). A first examination of the link between heart rate variability and networks of anxiety and depression symptoms. Journal of Psychophysiology, 37(4), 204–214. https://doi.org/10.1027/0269-8803/a000322
Walther, A., Kirschbaum, C., Wehrli, S., Rothe, N., Penz, M., Wekenborg, M., & Gao, W. (2023). Depressive symptoms are negatively associated with hair N-arachidonoylethanolamine (anandamide) levels: A cross-lagged panel analysis of four annual assessment waves examining hair endocannabinoids and cortisol. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 121, Article 110658. https://doi.org/10.1016/j.pnpbp.2022.110658
Wekenborg, M. K., Künzel, R. G., Rothe, N., Penz, M., Walther, A., Kirschbaum, C., Thayer, J. F., & Hill, L. K. (2023). Exhaustion and cardiovascular risk factors: the role of vagally-mediated heart rate variability. Annals of Epidemiology, 87, 93–99. https://doi.org/10.1016/j.annepidem.2023.09.008
2022
Aust, F., Beneke, T., Peifer, C., & Wekenborg, M. K. (2022). The relationship between flow experience and burnout symptoms: A systematic review. International Journal of Environmental Research and Public Health, 19(7), 3865. https://doi.org/10.3390/ijerph19073865
Walther, A., Mackens-Kiani, A., Eder, J., Herbig, M., Herold, C., Kirschbaum, C., Guck, J., Wittwer, L. D., Beesdo-Baum, K., & Kräter, M. (2022). Depressive disorders are associated with increased peripheral blood cell deformability: A cross-sectional case-control study (Mood-Morph). Translational Psychiatry, 12(1), Article 150. https://doi.org/10.1038/s41398-022-01911-3
Wekenborg, M. K., Schwerdtfeger, A., Rothe, N., Penz, M., Walther, A., Kirschbaum, C., Thayer, J. F., Wittling, R. A., & Hill, L. K. (2022). Determining the direction of prediction of the association between parasympathetic dysregulation and exhaustion symptoms. Scientific Reports, 12(1), Article 10648. https://doi.org/10.1038/s41598-022-14743-4
Wekenborg, M. K., Hill, L. K., Grabbe, P., Thayer, J. F., Kirschbaum, C., Lindenlaub, S., Arne Wittling, R., & von Dawans, B. (2022). Associations between burnout symptoms and social behaviour: Exploring the role of acute stress and vagal function. BMC Public Health, 22(1), 892. https://doi.org/10.1186/s12889-022-13333-3
Wekenborg, M. K., Schwerdtfeger, A., Aust, F., & Verkuil, B. (2022). High-frequency variability in heart rate is related to COVID-19-associated worries six years later. Biological Psychology, 173, 108404. https://doi.org/10.1016/j.biopsycho.2022.108404
2021
Rothe, N., Vogel, S., Schmelzer, K., Kirschbaum, C., Penz, M., Wekenborg, M. K., Gao, W., Walther, A. (2021). The moderating effect of cortisol and dehydroepiandrosterone on the relation between sleep and depression or burnout. Comprehensive Psychoneuroendocrinology, 100051. https://doi.org/10.1016/j.cpnec.2021.100051
Walther, A., Wehrli, S., Kische, H., Penz, M., Wekenborg, M. K., Gao, W., Rothe, N., Beesdo-Baum, K., & Kirschbaum, C. (2021). Depressive symptoms are not associated with long-term integrated testosterone concentrations in hair. The World Journal of Biological Psychiatry, 22(4), 288–300. https://doi.org/10.1080/15622975.2020.1795253
2020
Buruck, G., Pfarr, A. L., Penz, M., Wekenborg, M., Rothe, N., & Walther, A. (2020). The Influence of Workload and Work Flexibility on Work-Life Conflict and the Role of Emotional Exhaustion. Behavioral Sciences, 10(11), 174. https://doi.org/10.3390/bs10110174
Gao, W., Walther, A., Wekenborg, M., Penz, M., & Kirschbaum, C. (2020). Determination of endocannabinoids and N-acylethanolamines in human hair with LC-MS/MS and their relation to symptoms of depression, burnout, and anxiety. Talanta, 217, 121006. https://doi.org/10.1016/j.talanta.2020.121006
Rothe, N., Steffen, J., Penz, M., Kirschbaum, C., Walther, A. (2020). Examination of peripheral basal and reactive cortisol levels in major depressive disorder and the burnout syndrome: A systematic review. Neuroscience & Biobehavioral Reviews 114, 232–270. https://doi.org/10.1016/j.neubiorev.2020.02.024
Rothe, N., Schulze, J., Kirschbaum, C., Buske-Kirschbaum, A., Penz, M., Wekenborg, M. K., & Walther, A. (2020). Sleep disturbances in major depressive and burnout syndrome: A longitudinal analysis. Psychiatry Research, 286, 112868. https://doi.org/10.1016/j.psychres.2020.112868
Stächele, T., Domes, G., Wekenborg, M. K., Penz, M., Kirschbaum, C., & Heinrichs, M. (2020). Effects of a 6-week internet-based stress management program on perceived stress, subjective coping skills, and sleep quality. Frontiers in Psychiatry, 11(463). https://doi.org/10.3389/fpsyt.2020.00463
2019
Fleischhauer, M., Miller, R., Wekenborg, M. K., Penz, M., Kirschbaum, C., & Enge, S. (2019). Thinking against burnout? An individual’s tendency to engage in and enjoy thinking as a potential resilience factor of burnout symptoms and burnout-related impairment in executive functioning. Frontiers in Psychology,10(420). https://doi.org/10.3389/fpsyg.2019.00420
Gao, W., Penz, M., Wekenborg, M., Walther, A., & Kirschbaum, C. (2019). Determination of thyroid hormones in human hair with online SPE LC–MS/MS: Analytical protocol and application in study of burnout. Psychoneuroendocrinology, 106, 129–137. https://doi.org/10.1016/j.psyneuen.2019.03.032
Penz, M., Siegrist, J., Wekenborg, M. K., Rothe, N., Walther, A., & Kirschbaum, C. (2019). Effort-reward imbalance at work is associated with hair cortisol concentrations: Prospective evidence from the Dresden Burnout Study. Psychoneuroendocrinology, 109, 104399. https://doi.org/10.1016/j.psyneuen.2019.104399
Penz, M., Miller, R. A., Wekenborg, M. K., Walther, A., Rothe, N., Buske‐Kirschbaum, A. & Kirschbaum, C. (2019). Chronic stress exposure and altered leukocyte subsets: A shift model towards increased disease vulnerability. Psychoneuroendocrinology, 107, 10. https://doi.org/10.1016/j.psyneuen.2019.07.026
Penz, M., Miller, R. A., Wekenborg, M. K., Buske‐Kirschbaum, A. & Kirschbaum, C. (2019). Neutrophils and mediating glucocorticoids as potential link between adverse life events and increased risk for disease. Psychoneuroendocrinology, 100, 38. https://doi.org/10.1016/j.psyneuen.2018.12.134
Rothe, N., Schulze, J., Penz, M., Wekenborg, M. K., Walther, A. & Kirschbaum, C. (2019). Do burnout and depression show different sleep quality patterns and how does cortisol influence this association? Psychoneuroendocrinology, 100, 37. https://doi.org/10.1016/j.psyneuen.2018.12.132
Wekenborg, M.K., Hill, L.K., Thayer, J.F., Penz, M., Wittling, R.A., Kirschbaum, C. (2019). The Longitudinal Association of Reduced Vagal Tone with Burnout. Psychosomatic Medicine, 81(9), 791–798. https://doi.org/10.1097/PSY.0000000000000750.
Wekenborg, M.K., von Dawans, B., Hill, L.K., Thayer, J.F., Penz, M., Kirschbaum, C. (2019). Examining reactivity patterns in burnout and other indicators of chronic stress. Psychoneuroendocrinology, 106, 195–205. https://doi.org/10.1016/j.psyneuen.2019.04.002
2018
Penz, M., Wekenborg, M. K., Pieper, L., Beesdo-Baum, K., Walther, A., Miller, R., Stalder, T., & Kirschbaum, C. (2018). The Dresden Burnout Study: Protocol of a prospective cohort study for the bio-psychological investigation of burnout. International Journal of Methods in Psychiatric Research, e1613. https://doi.org/10.1002/mpr.1613
Penz, M., Kirschbaum, C., Buske-Kirschbaum, A., Wekenborg, M. K., & Miller, R. (2018). Stressful life events predict one-year change of leukocyte composition in peripheral blood. Psychoneuroendocrinology, 94, 17–24. https://doi.org/10.1016/j.psyneuen.2018.05.006
Wekenborg, M. K., Hill, L. K., Miller, R., Stalder, T., Thayer, J. F., Sophie Penz, M., & Kirschbaum, C. (2018). Reduced self-regulation mirrors the distorting effects of burnout symptomatology on task difficulty perception during an inhibition task. Stress, 1–9. https://doi.org/10.1080/10253890.2018.1479393
2017
Kanthak, M. K., Stalder, T., Hill, L. K., Thayer, J., Penz, M., & Kirschbaum, C. (2017). Autonomic dysregulation in burnout and depression: evidence for the central role of exhaustion. Scandinavian Journal of Work, Environment & Health, 43(5), 475–484. https://doi.org/10.5271/sjweh.3647
Penz, M., Stalder, T., Miller, R., Vera, M., Kanthak, M. K., & Kirschbaum, C. (2017). Hair cortisol as a biological marker for burnout symptomatology. Psychoneuroendocrinology. https://doi.org/10.1016/j.psyneuen.2017.07.485
Penz, M., & Walther, A. (2017). Wie gelangt Burnout in den Körper? - Mögliche Wege zur Somatisierung eines ursprünglich psychologischen Phänomens. Psychologie in Österreich, 242–250. https://doi.org/10.5167/uzh-223751
Interviews
- 01.10.2025 – Arte Dokumentation: https://www.arte.tv/de/videos/119121-006-A/psycho/
- 13.01.2025 – Interview Sächsische Zeitung: https://www.saechsische.de/wissen/regional/dresden-neue-corona-studie-der-uni-medizin-soll-erschoepfung-untersuchen-TMQWN7YH55BZDOETJM5EMQSFQE.html (paywall)
- 19.7.2023 – Interview ZDF Terra Explore Beitrag: https://youtu.be/z3185wqcJt4?feature=shared
- 23.01.2023 – ARD Dokumentation: https://www.ardmediathek.de/video/mein-koerper-oder-ard-wissen/mein-koerper-meine-energie-raus-aus-dem-tief/ard/Y3JpZDovL2Rhc2Vyc3RlLmRlL2FyZC13aXNzZW4vMjAyMy0wMS0yM18yMy0zMC1NRVo
Weitere Beiträge
Bigalke, K. (2020). Burnout – Im Leerlauf auf dem Gaspedal [Audio Podcast Episode]. In Echtzeit. Deutschlandradio. https://www.deutschlandfunkkultur.de/burnout-im-leerlauf-auf-dem-gaspedal-100.html
Honnigfort, B. (2019). Ausgebrannt, leer, kaputt. Frankfurter Rundschau. https://www.fr.de/ratgeber/gesundheit/ausgebrannt-leer-kaputt-11177964.html
Schumacher, H. (2016). Stressforscher: „Ein Burn-out lauert überall“. Berliner Morgenpost. https://www.morgenpost.de/web-wissen/article208225083/Stressforscher-Ein-Burn-out-lauert-ueberall.html